Showing 150+ publications · Sorted by date (newest first)
Multicenter Validation of a Combined Biomarker Panel for Early-Onset Sepsis in Preterm Neonates
Vasquez E, Tanaka Y, Lindgren A, Mitchell S, Sharma R, Ochieng J, et al.
Prospective study across 12 NICUs demonstrating 94% sensitivity and 89% specificity for a combination of IL-6, presepsin, and CRP measured at 6 hours of life for early-onset sepsis diagnosis in preterm neonates <32 weeks.
Antibiotic Duration for Culture-Negative Suspected Neonatal Sepsis: A Systematic Review and Meta-Analysis
Lindgren A, Mitchell S, Chen M, Al-Rashid F, et al.
Meta-analysis of 28 studies (n=12,450) showing no difference in adverse outcomes between 36-48h and 5-7 day empiric antibiotic courses in culture-negative suspected sepsis.
Global Patterns of Neonatal Sepsis Aetiology: First Report from the NSS International Sepsis Registry
Ochieng J, Santos M, Diallo A, Sharma R, Vasquez E, et al.
Analysis of 15,000 neonatal sepsis episodes across 45 centres in 30 countries, revealing marked geographic variation in causative organisms, resistance patterns, and mortality rates.
NSS Clinical Practice Guidelines for Neonatal Sepsis: 2025 Update
Newborn Sepsis Society Guideline Committee. Vasquez E, Ochieng J, Lindgren A, et al.
Comprehensive update of the NSS EOS and LOS guidelines incorporating novel biomarker evidence, revised antimicrobial recommendations, and AI-assisted risk stratification algorithms.
Machine Learning for Early Prediction of Neonatal Sepsis: A Multicentre Validation Study
Tanaka Y, Chen M, Mitchell S, Vasquez E, et al.
Development and external validation of a machine learning model using continuous vital sign monitoring data to predict sepsis onset 6-12 hours before clinical deterioration, with AUROC of 0.91.